InGex LLC
License fiscal year: 2000
Ohio State primary inventor(s): Alan Lambowitz
College: Arts and Sciences
Department: Molecular Genetics
Leadership: Paul Gold
Ownership status: Privately held
Headquarters: St. Louis, MO
Description: RNA-Seq provides comprehensive transcriptome profiling and allows for both mapping and quantifying transcriptome signatures associated with diseases. Ingex supplies two products utilizing a thermostable group II intron reverse transcriptase (TGIRT) for RNA-Seq, TGIRT™-III stand-alone enzyme and the TGIRT™ template-switching RNA-seq kit. TGIRT demonstrates several beneficial properties for RNA-Seq compared to the standard retroviral reverse transcriptase, including high fidelity, processivity, strand displacement activity, and proficient template-switching activity that is minimally dependent upon sequence. The company licenses proprietary technology from Ohio State and the University of Texas – Austin.
